Very nice Gerhardt. A comment or two- but of course its your RR your rules.
I love turn tables but they are massive real estate hogs. Consider eliminating it for an engine house, or another yard and some industries. A small town would look good in that space as well. I know you said running trains is key but that gets old quick. If you are set on keeping the TT then I agree with Ken on shifting the lead. You could also eliminate one or two whiskers on the bottom and add a short passing siding along the reversing loop, or a small yard with a couple of sidings. You didn't mention operating accessories but if you plan to use some they take up a lot of space so plan accordingly.
I see a lot of track and not enough storage space for cars too.
On the upper lever the reversing loop needs a second or once you reverse a train you can't turn it again without backing through the loop. Eliminating the reverse would open up more viewing of the lower level. Consider adding a set of turnouts so you can switch trains between the loops as well. Those long straights are perfect spots for the crossovers. This would allow you to park a train on the main and have another pass, very prototypical.
Good luck.
Bob
