While still in N, I bought a lot on eBay which turned out to have mostly Z scale items. I had been curious about Z, so I spent some time working on and in that tiny (2:220) scale.
I didn't find it much different from working in N; like anything else, regardless of scale, as long as you take your time and are deliberate, you can make it function quite well. To me the hardest part in working on these smaller scaled models is the lack of weight and mass: some part are so small (and light weight) that you literally can sneeze them into oblivion... 
I do find the mass and heft of S and O to be more satisfying...and I still use the Optivisor! 
Mark in Oregon 
