I know that Lionel uses the new Legacy system for most of it's newer products. Don't know if Lionel Legacy or TMCC will work with DCC.
DCC might be an MTH only thing in S scale.
One comment about the size of your layout is you have a bit more space in your room then I have and I am running mainly O gauge trains, with an A.F. 2 rail track on the inside of my O gauge tracks.
Lee Fritz