We have at least two long distance Amtrak runs in Pennsylvania. East-West kinda.
The Pennsylvanian. Points west/Pittsburgh/points east to Philadelphia. Car via PA turnpike I76 (Pittsburgh to Phily, north subs. about 5 1/2 hrs).
The Capitol Limited. Points west/or east/ Pittsburgh/ over the mountains eventually to Washington DC. Car via PA turnpike I76 and I 70 south about the same 4 to 5 hrs.
Note that traffic, I76 (Turnpike), and I70 has become much more intense the last few years. Eventually Baltimore/Washington DC you access the dreaded I95. (speed average, may be, 30 mph at times).
DC area has other rail transit. I think.
Recently Allegheny County/Pittsburgh airport authority announced a 2 billion dollar terminal make-over. Most interesting design, that eliminates the people mover land side/ air side. Air planes are not going away. IMO.
Could be wrong and often, Mike CT.