Cody. Tom's response is excellent, it really depends on what you want to do. Others on this site are much more knowledgeable than me, but I thought I might add that Lionel has made available many different engines and cars over the years, and hopefully will continue to do so. A few items by Lionel had problems for sure and I have experienced this, but the vast majority for me have been very good.
American Models has beautiful and well made variety of engines and cars. And then SHS, MTH along with a great many American Flyer original equipment is available on the secondary market. As others will note accurately, nothing compared to the offerings and manufacturers for O Gauge, but in my instance enough for me. These are some of my collection, just because a picture is worth a thousand words as they say. I am blessed to have these and more. Good luck. Mike