I wanted to be more careful/precise about my measurements in track center spacing, as this is important in actual train operation with clearances for two trains on parallel tracks. This shows a center-rail spacing of 4.25" between FasTrack O36 and my O44.5 compound curve arrangement used in this layout. (Generated using AnyRail).
You can see that the outside O44.5 is not perfectly circular (as expected), with the spacing at the widest point (bottom in this illustration) a bit more than 4.25 at 4.5". Spacing larger is fine, as long as it is nowhere less than 4.25".