The wheels don't care what the power source is. What's inside the locomotive does. As to command control, other than Linoel's FlyerChief, there's Lionel's TMCC/Legacy, MTH's DCS and DCC.
Lionel's recent Legacy locomotives are DCC compatible as are MTH's DCS locomotives. While neither system offers all the functionality of a dedicated DCC decoder, the basic DCC functions are there along with a couple of options.