So, I was giving this some thought last night, and while I wanted a layout that could wrap around the walls, it was going to be a tight fit between this behemoth, and the wall opposite (especially if I wanted a railyard). I thought that instead of trying to cram in so much rail (which I've probably already done), I should plan for some scenery as well, and give me and my boys "tasks". So, added a couple more sidings at the top (for steam and diesel maintenance, and can also double as an Inglenook Switch Puzzle), a siding at the bottom (for passenger and freight service) and two sidings internal to the double reverse. These will be able to store LC/LC+ trains when I power them down, but also I'll put industry alongside (thinking chemical plants) the tracks. Here is what I came up with. Pretty pleased with myself, and if I place it in the middle of the room, I will have a problem reaching potentially only the very middle, but that's it.
Not to mention the O27 upper loop I plan to add to it as well to run a subway when I can get my hands on a good one.