The more affordable 1/43 cars are mass produced, low on specific details, popular makes & models, and often available label in many non-prototypical paint colors. Road Champs, Ertl, Matchbox, & K-Line cars are examples.
The more expensive 1/43 cars are limited production, loaded with specific details, often less popular makes & models, and usually only available in prototypical factory OEM paint colors. These are primarily targeted at the car collector market (whose members aren't spending any $ on locomotives). Corgi, Brookline, & Eastwood are examples.