I would reload the remote software.
My main remote had so many old consists built under older DCS versions, that I reset it and started over. I did house cleaning inside a few times but I think there were missing addresses and other weird things going on. It was full and I was using all the addresses available.
Now, I also moved all G scale to a dedicated remote helping to free up those used addresses.
I also noticed a brief time that new batteries went dead on me. Because I was resetting and changing remotes, I wasn't sure what exactly happened. I attributed it to all the moving and work with the remote. Batteries seem to be fine now.