it can possibly be cleaned but I would guess the fecal coly would stain the finish permently. maybe try dawn dish soap with warm water and then immediately dry in a heated area .with most of water dried off as best you can then let the train dry in oven after it was shut off and just warm but not hot! I wouldn't be surprised that mice got into the boxes and left mouse fecal coly and also urinated on everything and the will RUST the trains if they were made form metal !