On my layout, I went for a completely "glass cockpit"; using the iPad (or Cab2). No physical switches, controls panels, etc. I can always add a control panel later, but as of now, I am happy with the results. I like the clean, change-able, iPad or Cab2 control for the layout.
Disclaimer: I helped develop LCS. Although I am a hobbyist and I am being honest with my thoughts and my execution on my layout.