Thanks for that! Those really turned out nice.
If they do one in Santa Fe, then I would order it. They would just need to enlarge that one lower window so that all 4 are the same size, and add the breaker bars in front and back of the dome. Then it would be spot on for the 506-513 series Santa Fe big dome. But the Lionel window arrangement is correct as is for the Santa Fe 550-555 series big dome. They just need the breaker bars in front and back of the dome.
It would also be easy for Lionel to offer a pretty complete Santa Fe mid 1950's "San Francisco Chief" consist using their existing tooling with that big dome car, some coaches, sleepers, two diners, and a couple of head end cars. The same would work for a Santa Fe mid 1950's "The Chief" consist if the big dome lower window is enlarged, and a chair car/parlor observation would also be appropriate for that consist, or perhaps a sleeper observation in the first years of the big dome on that train.
*(EDITED TO UPDATE FOLLOWING FURTHER RESEARCH)