How big is your layout, how much track?
Personally, I think the Z4000 is overkill. I expect you can get great results if you used a Lionel Powerhouse PH-180 and save some cash:
Z4000:
http://www.modeltrainstuff.com...er-p/mth-40-4000.htm
PH-180:
http://www.modeltrainstuff.com...ly-p/lio-6-22983.htm
(out of stock at MB Klein)
The good thing about the PH-180 is you won't be applying too much voltage if you run any TMCC engines (18VAC max recommended), not sure what the Z4000 output voltage is (I only have the Z750, it's 21VAC and I no longer use it).
Hope this helps!