One thing that may help is to look at pre-existing track designs from a variety of Internet sources and train sites to get your mind focused on what looks good and may fit into your area. Lionel, MTH and Atlas all have various designs on their web pages. There are also lots of great designs on this Forum by our "resident" designers that you can look at for inspiration.
After looking at a variety of designs, you should be able to narrow down what you want to incorporate into your own layout and add, subtract and modify to make it work.