I suspect that the trolley car in the above photo is eastbound towards the Delaware Water Gap on Rt 611.
Today's Route 611 was once where the Stroudsburg, Water Gap & Portland Railway, a trolley line that provided a scenic ride from Stroudsburg, PA ran through the Delaware Water Gap and ended just north of the Lehigh & New England's tracks in Portland. This trolley line was controlled by the Lehigh Valley Traction Company (better know for its Liberty Bell Limited), which had dreams of providing service all the way from the 69th Street Terminal at the edge of Philadelphia directly to the resorts in the Delaware Water Gap. However the Lehigh & New England prevented the line from crossing its tracks, thus requiring passengers and their bags to get off of one car, walk a block across the L&NE and then resume their journey. The combination of the general decline in trolley car line fortunes, the transfer in Portland, and the superior service offered by the PRR from Philadelphia via the Belvidere-Delaware Line and trackage rights on the Delaware, Lackawanna & Western to Stroudsburg doomed the line.
In 1926 the DL&W cancelled the lease of land that allowed the SWG&P to operate through the Gap. By now renamed the Stroudsburg Traction Company, all service ended in 1928.