I would also be concerned about single directional running. Here’s my limited but ongoing experience.
I have a 6 x 16 layout (similar to your space) that narrows to 4 ft wide in the middle to accommodate a future control board and operator space. My initial track config was nested 054 and 042 loops with one reversing loop, several spurs for accessories and a long trolley line. The main loops were connected to each other at one point. I could run two trains simultaneously. If running one train it could change directions once without reversing. I posted it on the forum and asked for opinions. Someone suggested I might lose interest in watching two trains loop around continuously. I agreed so I made major changes.
Attached are pictures of the current config. It now has two nested loops that converge at one point and a long passing siding. There are two reversing loops. Only one train can run at a time but it can go anywhere in any direction without reversing. I can store one train while running another and switch them out using the sidings. Running is interesting and fun but can be pretty harrowing at times. Definitely not boring.
I don’t know if this is the final layout, probably not. I want to build mountains, tunnels and bridges at some point. The wiring stays on the table top until I decide. 
