I'd try plugging the base back in and see if DCS still works ok. Keep the TMCC locomotives off any powered track just to isolate the issue.
I've noticed no issue from the TMCC base on my layout interfering with DCS but some TMCC locomotives will. I've mostly had an issue when 3 TMCC locomotives are powered and more than one PS2 locomotive is powered up. Then I'll have DCS signal loss issues in some spots. Park one of the TMCC locomotives on an unpowered siding and everything is fine again.