There is an identified issue where it's possible that the TMCC signal will affect the DCS signal. It's not a certain thing, and it does seem that the layout wiring has a significant effect on the issue. Adrian has posted in some detail about the interactions, and he's also set about trying to engineer a solution to the issue for his club. I ran DCS and TMCC on around 180 feet of track (Fastrack) in my old house with no issues of interaction at all, so it's not a sure thing. Also, tons of folks run DCS and TMCC/Legacy together with no issues.
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