I would say that the speed at which a fast clock runs should depend on the size (not the scale) of the layout on which it's running. Running at the same scale-speed, a train will take longer to run between towns on a large layout than a small one. If the full scale running time is one hour in the real world, the clock has to run more slowly on the larger layout. This is just a theoretical answer. I would never bother with it in running my own layouts.
MELGAR