I double headed my 408e’s this weekend with DCS for the first time, as a test...and it worked great!
Since I am powering the STG layout through my O Gauge layout, I run these shiny monsters from my IPhone or IPad via the DCS WI-FI, it is really the way to go. I know “I will shoot my eye out”, but hey it’s really fun.
I powered the STG layout by simply running a track power wire from a lock on to my O gauge yard power distribution panel, and accessory power via a wire from my STG accessory distribution panel to my O gauge yard accessory power distribution panel. Easy peasy, two wires, and NO charge for extra equipment.
I was using a modern lighted lock on but the ladder on my 381e kept hitting it, so I switched to the unlit lower profile UTC lock on, problem solved.