I don't think we will see them, but my list of wants remains the same:
(All new scale tooling with scale wheel/coupler options)
GP-30
GP-7/9
SD-7/9
SD-40-2
RS-1
SW/NW/MP switchers
Pretty much any steam from an 0-4-0 to 4-8-4. Take a pause on the Giant articulated models for a spell.
I could go on and on, but those would be high on my list.
Most important though is that Lionel should ABSOLUTELY produce scale passenger cars with the nifty spring loaded coupler that they have used in O on the S-3 and the new Autoracks.