Intuitive and easiest to use, I believe, are going to be a matter of personal choice. If the program includes a Fastrack library then it will probably be an option for you. The 3 I have tried are Anyrail, RR-Track and SCARM. Of those I believe SCARM and Anyrail have trial versions. As I recall you still have to purchase RR-Track to try it out.
SCARM has really gained in popularity the last couple of years. There are some very well versed SCARM users here on the forum as well. I haven't followed Anyrail too much, but they have had some updates over the years and it was fairly easy as I recall. RR-Track still has some sort of bug that causes it to crash every once in a while. That's been improved, but still happens infrequently. RR-Track seems kind of like a forgotten program as far as a modern interface and regular updates. RR-Track has a lot of libraries, but they are all at extra cost after you select your initial version (they have some packages that include selected libraries for initial purchase).
I have seen some very impressive layouts posted here on the forum that were created with each one of the three I mentioned above. There are some very talented users of each program that visit and post on the forum. Each program is capable of creating very nice layout plans.